/ June 15, 2019/ English, MacroGard/ 0 comments

MacroGard – Immunomodulator for Animals

MacroGard® is a highly purified and exposed β-1,3/1,6 -Glucans with high biological activity preserved. From a unique and special yeast, Saccharomyces Cerevisiae, through extraction of a small and selected portion of its structure the purest form of β-1,3/1,6 -Glucans is obtained. The greatest challenge in the extraction of β-Glucans is the careful preservation of their molecular structure which is essential for maintaining their bioactivity.

After years of research, Biorigin developed advanced techniques that today yield a product with high levels of natural purified in bioactive β-1,3/1,6 -GlucansMacroGard® .

MacroGard® can be readily added to animal feeds, premixes and supplements that will be used for feeding fish, shrimp, dogs, cats, horses, cattle, pigs, poultry and small ruminants.

When ingested by animal, β-1,3/1,6 -Glucans are not affected by the enzymes and pH in the mouth and stomach, arriving intact in intestines. In the intestine, β-1,3/1,6 -Glucans bind to specific receptors on the surface of macrophages which then phagocyte β-1,3/1,6 -Glucans and become more active and better prepared to internalize digests and destroy pathogens. Macrophage breakdown β-1,3/1,6 -Glucans molecules into smaller bioactive particles and produce large amounts of cytokines. β-1,3/1,6 -Glucans and cytokines activate and enhance the defense cells of the body as a whole. Lysozymes, another antimicrobial peptides are also intensively produced enhancing the natural body defense potential. They release the cytokines activate lymphocytes which produce antibodies. This chain reaction prepares the entire ironmen system for the rapid and efficient elimination of pathogens. All these protection mechanisms work synergistically to allow animals to face environmental challenges.

Whenever an animal suffers an attack by pathogens or any situation that promotes inflammation, its immune response may range from aggressive inflammation to a very low resistance level called Immuno-suppression. MacroGard® is able to modulate this body response promoting an effective reaction of the immune system and maintaining the animals’ health and performance until infection is eradicated.

How then does the use of MacroGard® affect the routine of pets and livestock production? By providing balanced natural defences resistance to disease and welfare. MacroGard® promotes excellent health and outstanding performance of the animals, higher survival rates in Salmons, Nile Tilapias, Pacus and Shrimps submitted to challenges. Studies show up to 55 percent higher weight gain in Nile Tilapia, Dogs present higher antibody levels after vaccination in addition to rapid recovery of the defense system after any kind of stress, reduces itching and skin scaling as well as hair loss in dogs with dermatitis, it also aids dogs with pain due to joint inflammation making them more active and providing a better quality of life. Enhances endurance to training and transport. Improves colostrum quality promoting full development. Boost vaccine and response.

MacroGard® improves the performance of Poultry, Pigs and Ruminants and contributes to the increase in the production of antibodies in these species.

Investing in MacroGard® is to invest in a natural solution to improve the health and the quality of life of your animals, and this investment is immediately paid by the better health of your pets, the higher productivity of your farm and increase the profits for you.

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